In 1990 the Commission of the European Union laid down the procedure for establishing maximum residue limits (MRLs) of veterinary drugs in foodstuffs of animal origin. This is to protect consumers and the public health. The use of antibiotics leads to the possibility of resistance in target pathogens and must be controlled. The Regulation has four Annexes. Annex IV lists the drugs for which no MRLs can be set because the drugs are regarded as too dangerous. These drugs are chloramphenicol, recently found in Chinese honey, nitrofurans including furazolidone, ronidazole, dapsone, dimetridazole, colchicine, chlorpromazine, chloroform and metronidazole.